Examples may include antibiotics for infections. Faithfull ... I’ve got a slightly enlarged liver. Pain and bloating. End stage liver cancer also leads to abdominal pain. In general, liver pain is a consequence of liver disease (a group of conditions / disorders that cause liver inflammation or liver damage). Thanks. Irritable bowel syndrome is a condition in which bouts of tummy pain are associated with bloating and changes in bowel habit such as constipation and diarrhoea. Since you suspect liver pain it is prudent to try to see a liver specialist, but there are a lot things that cause complex gastro symptoms and everyone is different. Persistent bloating along with other symptoms such as severe abdominal pain, fever, or blood in your stool might be a sign of a more serious health issue than just bloating from a bad meal. Just to complicate matters further, the amount of bloating does not relate to the seriousness of the cause. Treatments for abdominal bloating and pain will address the underlying condition. In the late stages of liver cancer, the tumor invades a number of tissues throughout the abdomen, leading to massive organ damage and abdominal pain. Bloating is usually nothing to worry about, but in some cases it can be a sign of ovarian cancer, bowel obstruction, liver disease, and other conditions. For most things a healthy diet is key so cutting out sugar is certainly good. Is feeling bloated common? Health issues such as cancer, liver disease, inflammatory bowel disease, and other conditions can cause severe bloating. Pain associated with late stage liver disease is usually treated with analgesics such as morphine. See the separate leaflet called Irritable Bowel Syndrome.